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  5. A European Respiratory Society technical standard: exhaled biomarkers in lung disease

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Article
en
2017

A European Respiratory Society technical standard: exhaled biomarkers in lung disease

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en
2017
Vol 49 (4)
Vol. 49
DOI: 10.1183/13993003.00965-2016

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Peter J Barnes
Peter J Barnes

Imperial College London

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Ildikó Horváth
Peter J Barnes
Stelios Loukides
+39 more

Abstract

Breath tests cover the fraction of nitric oxide in expired gas (FeNO), volatile organic compounds (VOCs), variables in exhaled breath condensate (EBC) and other measurements. For EBC and for FeNO, official recommendations for standardised procedures are more than 10 years old and there is none for exhaled VOCs and particles. The aim of this document is to provide technical standards and recommendations for sample collection and analytic approaches and to highlight future research priorities in the field. For EBC and FeNO, new developments and advances in technology have been evaluated in the current document. This report is not intended to provide clinical guidance on disease diagnosis and management.Clinicians and researchers with expertise in exhaled biomarkers were invited to participate. Published studies regarding methodology of breath tests were selected, discussed and evaluated in a consensus-based manner by the Task Force members.Recommendations for standardisation of sampling, analysing and reporting of data and suggestions for research to cover gaps in the evidence have been created and summarised.Application of breath biomarker measurement in a standardised manner will provide comparable results, thereby facilitating the potential use of these biomarkers in clinical practice.

How to cite this publication

Ildikó Horváth, Peter J Barnes, Stelios Loukides, Peter J. Sterk, Marieann Högman, Anna‐Carin Olin, Anton Amann, Balázs Antus, Eugenio Baraldi, András Bikov, Agnes W. Boots, Lieuwe D. J. Bos, Paul Brinkman, Caterina Bucca, Giovanna Elisiana Carpagnano, Massimo Corradi, Simona M. Cristescu, Johan C. de Jongste, Anh Tuan Dinh‐Xuan, Edward Dompeling, Niki Fens, Stephen J. Fowler, Jens M. Hohlfeld, Olaf Holz, Quirijn Jöbsis, Kim van de Kant, Hugo Knobel, Κonstantinos Κostikas, Lauri Lehtimäki, Jon O. Lundberg, Paolo Montuschi, Alain Van Muylem, Giorgio Pennazza, Petra Reinhold, Fabio Luigi Massimo Ricciardolo, Philippe Rosias, Marco Santonico, Marc P. van der Schee, Frederik‐Jan van Schooten, Antonio Spanevello, Thomy Tonia, T.J. Vink (2017). A European Respiratory Society technical standard: exhaled biomarkers in lung disease. , 49(4), DOI: https://doi.org/10.1183/13993003.00965-2016.

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Publication Details

Type

Article

Year

2017

Authors

42

Datasets

0

Total Files

0

Language

en

DOI

https://doi.org/10.1183/13993003.00965-2016

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