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The last 5 uploaded publications
Negative regulation of Toll-like receptor-mediated immune responses
Foo Y. Liew, Damo Xu, Elizabeth Brint, Luke O'neill (2005). Negative regulation of Toll-like receptor-mediated immune responses. Nature reviews. Immunology, 5(6), pp. 446-458, DOI: 10.1038/nri1630.
Article272 days agoMal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
Katherine A. Fitzgerald, Eva M. Pålsson‐McDermott, Andrew Bowie, Caroline A. Jefferies, Ashley Mansell, Gareth Brady, Elizabeth Brint, Aisling Dunne, Pearl Gray, Mary T. Harte, Diane McMurray, Dirk E. Smith, John E. Sims, Timothy A. Bird, Luke O'neill (2001). Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature, 413(6851), pp. 78-83, DOI: 10.1038/35092578.
Article272 days agoST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
Elizabeth Brint, Damo Xu, Haiying Liu, Aisling Dunne, Andrew N. J. McKenzie, Luke O'neill, Foo Y. Liew (2004). ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nature Immunology, 5(4), pp. 373-379, DOI: 10.1038/ni1050.
Article272 days agoBruton's Tyrosine Kinase Is a Toll/Interleukin-1 Receptor Domain-binding Protein That Participates in Nuclear Factor κB Activation by Toll-like Receptor 4
Caroline A. Jefferies, Sarah Doyle, Cornelia Brunner, Aisling Dunne, Elizabeth Brint, Claudia Wietek, Eva Walch, Thomas Wirth, Luke O'neill (2003). Bruton's Tyrosine Kinase Is a Toll/Interleukin-1 Receptor Domain-binding Protein That Participates in Nuclear Factor κB Activation by Toll-like Receptor 4. Journal of Biological Chemistry, 278(28), pp. 26258-26264, DOI: 10.1074/jbc.m301484200.
Article272 days agoTrif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling
Anne F. McGettrick, Elizabeth Brint, Eva M. Pålsson‐McDermott, Daniel C. Rowe, Douglas T. Golenbock, Nicholas J. Gay, Katherine A. Fitzgerald, Luke O'neill (2006). Trif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling. Proceedings of the National Academy of Sciences, 103(24), pp. 9196-9201, DOI: 10.1073/pnas.0600462103.
Article272 days ago