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The last 5 uploaded publications
Anti-restriction functions of injected phage proteins revealed by peeling back layers of bacterial immunity
Sukrit Silas, Héloïse Carion, Kira S. Makarova, David Sanchez Godinez, Surabhi Haniyur, Lucy Volino, Wearn‐Xin Yee, Andrea Fossati, Danielle L. Swaney, Michael Bocek, Eugene V Koonin, Joseph Bondy‐Denomy (2025). Anti-restriction functions of injected phage proteins revealed by peeling back layers of bacterial immunity. , 16(1), DOI: https://doi.org/10.1038/s41467-025-63056-3.
Article147 days agoActivation of bacterial programmed cell death by phage inhibitors of host immunity
Sukrit Silas, Héloïse Carion, Kira S. Makarova, Eric Laderman, Thomas C. Todeschini, Pradeep Kumar, Matthew C. Johnson, Michael Bocek, Franklin L Nobrega, Eugene V Koonin, Joseph Bondy‐Denomy (2025). Activation of bacterial programmed cell death by phage inhibitors of host immunity. , 85(9), DOI: https://doi.org/10.1016/j.molcel.2025.04.010.
Article147 days agoSupplementary_Table_4_RT_loci_spacer_hits.xlsx
Kira S. Makarova, Sergey Shmakov, Sukrit Silas, Eugene V Koonin, Andrew FireSupplementary_Table_4_RT_loci_spacer_hits.xlsx. , DOI: https://doi.org/10.6084/m9.figshare.5051755.
Dataset147 days agoSupplementary_Table_1_RT_cas_loci_details.xlsx
Kira S. Makarova, Sergey Shmakov, Eugene V Koonin, Sukrit Silas, Andrew FireSupplementary_Table_1_RT_cas_loci_details.xlsx. , DOI: https://doi.org/10.6084/m9.figshare.5051719.
Dataset147 days agoA Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition
Georg Mohr, Sukrit Silas, Jennifer L. Stamos, Kira S. Makarova, Laura M. Markham, Jun Yao, Patricia Lucas‐Elío, Antonio Sánchez-Amat, Andrew Fire, Eugene V Koonin, Alan M. Lambowitz (2018). A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. , 72(4), DOI: https://doi.org/10.1016/j.molcel.2018.09.013.
Article147 days ago