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The last 5 uploaded publications
Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors
Xujie Zhang, Lin Sun, Megan E. Meuser, Waleed A. Zalloum, Shujing Xu, Tianguang Huang, Srinivasulu Cherukupalli, Xiangyi Jiang, Xiao Ding, Yucen Tao, Dongwei Kang, De Clercq Erik, Christophe Pannecouque, Alexej Dick, Simon Cocklin, Xinyong Liu, Peng Zhan (2021). Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors. , 226, DOI: https://doi.org/10.1016/j.ejmech.2021.113848.
Article36 days agoDesign, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities
Lin Sun, Alexej Dick, Megan E. Meuser, Tianguang Huang, Waleed A. Zalloum, Chin‐Ho Chen, Srinivasulu Cherukupalli, Shujing Xu, Xiao Ding, Ping Gao, Dongwei Kang, De Clercq Erik, Christophe Pannecouque, Simon Cocklin, Kuo‐Hsiung Lee, Xinyong Liu, Peng Zhan (2020). Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities. , 63(9), DOI: https://doi.org/10.1021/acs.jmedchem.0c00015.
Article36 days agoStructure-based design of novel 2,4,5-trisubstituted pyrimidine derivatives as potent HIV-1 NNRTIs by exploiting the tolerant regions in NNTRIs binding pocket
Zhenzhen Zhou, Minghui Xie, Zongji Zhuo, Yalin Wang, Fabao Zhao, Sining Tao, Zhening Liang, De Clercq Erik, Christophe Pannecouque, Shujing Xu, Dongwei Kang, Xinyong Liu (2025). Structure-based design of novel 2,4,5-trisubstituted pyrimidine derivatives as potent HIV-1 NNRTIs by exploiting the tolerant regions in NNTRIs binding pocket. , 289, DOI: https://doi.org/10.1016/j.ejmech.2025.117464.
Article36 days agoDesign, synthesis and structure-activity relationships of novel HIV capsid inhibitors with potent antiviral activities
Dazhou Shi, Shujing Xu, Lin Sun, Prem P. Sharma, Brijesh Rathi, Mei Wang, Linan Wu, Xiangyi Jiang, De Clercq Erik, Christophe Pannecouque, Xinyong Liu, Alexej Dick, Shujing Xu (2025). Design, synthesis and structure-activity relationships of novel HIV capsid inhibitors with potent antiviral activities. , 295, DOI: https://doi.org/10.1016/j.ejmech.2025.117784.
Article36 days agoDesign, synthesis and structure-activity relationships of novel HIV capsid inhibitors with potent antiviral activities
Dazhou Shi, Shujing Xu, Lin Sun, Prem P. Sharma, Brijesh Rathi, Mei Wang, Linan Wu, Xiangyi Jiang, De Clercq Erik, Christophe Pannecouque, Xinyong Liu, Alexej Dick, Shujing Xu (2025). Design, synthesis and structure-activity relationships of novel HIV capsid inhibitors with potent antiviral activities. , 295, DOI: https://doi.org/10.1016/j.ejmech.2025.117784.
Article36 days ago