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The last 5 uploaded publications
Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation
Susanna K. Elledge, Hai L. Tran, Alec H. Christian, Veronica Steri, Byron Hann, Dean Toste, Christopher J Chang, James A. Wells (2019). Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation. , DOI: https://doi.org/10.1101/748160.
Preprint107 days agoA Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation
Alec H. Christian, Jia Shang, Patricia Zhang, Arismel Tena Meza, Matthew S. Sigman, Christopher J Chang, Dean Toste (2019). A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation. , DOI: https://doi.org/10.26434/chemrxiv.8176823.v1.
Preprint107 days agoA Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation
Alec H. Christian, Jia Shang, Patricia Zhang, Arismel Tena Meza, Matthew S. Sigman, Christopher J Chang, Dean Toste (2019). A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation. , DOI: https://doi.org/10.26434/chemrxiv.8176823.
Preprint107 days agoA Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation
Alec H. Christian, Shang Jia, Wendy Cao, Patricia Zhang, Arismel Tena Meza, Matthew S. Sigman, Christopher J Chang, Dean Toste (2019). A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation. , 141(32), DOI: https://doi.org/10.1021/jacs.9b04744.
Article107 days agoMethionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
Dan He, Huijin Feng, Belen Sundberg, Jiaxing Yang, Justin L. Powers, Alec H. Christian, John E. Wilkinson, Cian Monnin, Daina Avizonis, Craig J. Thomas, Richard A. Friedman, Michael D. Kluger, Michael A. Hollingsworth, Paul M. Grandgenett, Kelsey Klute, Dean Toste, Christopher J Chang, Iok In Christine Chio (2022). Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis. , 82(16), DOI: https://doi.org/10.1016/j.molcel.2022.06.005.
Article107 days ago