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The last 5 uploaded publications
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Nick Dand, Philip E. Stuart, John Bowes, David Ellinghaus, Joanne Nititham, Jake Saklatvala, Maris Teder‐Laving, Laurent F. Thomas, Tanel Traks, Steffen Uebe, G. Aßmann, David Baudry, Frank Behrens, Allison C. Billi, Matthew A. Brown, Harald Burkhardt, Francesca Capon, Raymond T. Chung, Charles Curtis, Michael Duckworth, Eva Ellinghaus, Oliver FitzGerald, Sascha Gerdes, Christopher Em Griffiths, Susanne Gulliver, Philip Helliwell, Pauline Ho, Per Hoffmann, Oddgeir L. Holmen, Zhiming Huang, Kristian Hveem, Deepak R. Jadon, Michaela Köhm, Cornelia Kraus, Céline Lamacchia, Sang Hyuck Lee, Feiyang Ma, Satveer K. Mahil, Neil McHugh, Ross McManus, Ellen Heilmann Modalsli, Michael J. Nissen, Markus M. Nöthen, Vinzenz Oji, Jorge R. Oksenberg, Matthew T. Patrick, Bethany E. Perez White, Andreas Ramming, Jürgen Rech, Cheryl F. Rosen, Mrinal K. Sarkar, Georg Schett, Börge Schmidt, Trilokraj Tejasvi, Heiko Traupe, John J. Voorhees, Eike Matthias Wacker, Richard B. Warren, Rachael Bogle, Stephan Weidinger, Xiaoquan Wen, Zhaolin Zhang, A. David Burden, Catherine Smith, Sara Brown, Satveer K. Mahil, Helen McAteer, Julia Schofield, Stefan Siebert, Andres Metspalu, Lili Milani, Mari Nelis, Anne Barton, Vinod Chandran, Tõnu Esko, John Foerster, André Franke, Dafna D. Gladman, Jóhann E. Guðjónsson, Wayne Gulliver, Ulrike Hüffmeier, Külli Kingo, Sulev Kõks, Wilson Liao, Mari Løset, Reedik Mägi, Rajan P. Nair, Proton Rahman, André Reis, Catherine Smith, Paola Di Meglio, Juliet N. Barker, Lam C. Tsoi, Michael A. Simpson (2025). GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets. , 16(1), DOI: https://doi.org/10.1038/s41467-025-56719-8.
Article57 days agoGWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Nick Dand, Philip E. Stuart, John Bowes, David Ellinghaus, Joanne Nititham, Jake Saklatvala, Maris Teder‐Laving, Laurent F. Thomas, Tanel Traks, Steffen Uebe, G. Aßmann, David Baudry, Frank Behrens, Allison C. Billi, Matthew A. Brown, Harald Burkhardt, Francesca Capon, Raymond T. Chung, Charles Curtis, Michael Duckworth, Eva Ellinghaus, Oliver FitzGerald, Sascha Gerdes, Christopher Em Griffiths, Susanne Gulliver, Philip Helliwell, Pauline Ho, Per Hoffmann, Oddgeir L. Holmen, Zhiming Huang, Kristian Hveem, Deepak R. Jadon, Michaela Köhm, Cornelia Kraus, Céline Lamacchia, Sang Hyuck Lee, Feiyang Ma, Satveer K. Mahil, Neil McHugh, Ross McManus, Ellen Heilmann Modalsli, Michael J. Nissen, Markus M. Nöthen, Vinzenz Oji, Jorge R. Oksenberg, Matthew T. Patrick, Bethany E. Perez White, Andreas Ramming, Jürgen Rech, Cheryl F. Rosen, Mrinal K. Sarkar, Georg Schett, Börge Schmidt, Trilokraj Tejasvi, Heiko Traupe, John J. Voorhees, Eike Matthias Wacker, Richard B. Warren, Rachael Wasikowski, Stephan Weidinger, Xiaoquan Wen, Zhaolin Zhang, Anne Barton, Vinod Chandran, Tõnu Esko, John Foerster, André Franke, Dafna D. Gladman, Jóhann E. Guðjónsson, Wayne Gulliver, Ulrike Hüffmeier, Külli Kingo, Sulev Kõks, Wilson Liao, Mari Løset, Reedik Mägi, Rajan P. Nair, Proton Rahman, André Reis, Catherine Smith, Paola Di Meglio, Juliet N. Barker, Lam C. Tsoi, Michael A. Simpson, James T. Elder (2023). GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets. , DOI: https://doi.org/10.1101/2023.10.04.23296543.
Preprint57 days agoDevelopment of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove
Teresa Tsakok, Jake Saklatvala, Theo Rispens, Floris C. Loeff, Annick de Vries, Michael H. Allen, Inês A. Barbosa, David Baudry, Tejus Dasandi, Michael Duckworth, Freya Meynell, Alice Russell, Anna Chapman, Sandy McBride, Kevin E. McKenna, Gayathri Perera, Helen Ramsay, Raakhee Ramesh, Kathleen M. Sands, Alexa R. Shipman, A. David Burden, Christopher Em Griffiths, Nick J. Reynolds, Richard B. Warren, Satveer K. Mahil, Juliet N. Barker, Nick Dand, Catherine Smith, Michael A. Simpson (2023). Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove. , 8(4), DOI: https://doi.org/10.1172/jci.insight.156643.
Article57 days agoIntegrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics
Ali Al‐Janabi, Paul Martin, Adnan R. Khan, Amy Foulkes, Catherine Smith, Christopher Em Griffiths, Andrew P. Morris, Stephen Eyre, Richard B. Warren, Shehnaz Ahmed, Oras Alabas, Juliet N. Barker, G Becher, Anthony Bewley, Ian M. Evans, Philip Hampton, Brian Kirby, Elise Kleyn, Philip Laws, Linda Lawson, Teena Mackenzie, Kathleen McElhone, Tess McPherson, Simon Morrison, Caroline Owen, Eleanor Pearson, Amir Rashid, Nick J. Reynolds, Anja Strangfeld, Shernaz Walton, Zenas Z N Yiu, Girish Kumar Gupta, Anja Strangfeld, Richard Weller, Vera Zietemann, Nadia Aldoori, Mahmud Ali, Ahmed Al-Rusan, Caroline Angit, Alex Anstey, F. C. Antony, Charles W. Archer, Suzanna August, Periasamy Balasubramaniam, David Baudry, Kay Baxter, Anthony Bewley, Alexandra Bonsall, Sara Brown, Victoria Brown, David Burden, Ekaterina Burova, Aamir Butt, Anna Chapman, S. Cliff, Mihaela Costache, S. Darné, Claudia DeGiovanni, Trupti Desai, Victoria Diba, Eva Domanne, Michael Duckworth, Harvey Dymond, Caoimhe Fahy, Susanne Farwer, Leila Ferguson, Maria‐Angeliki Gkini, Alison Godwin, J. M. R. Goulding, Fiona Hammonds, Shaheen Haque, Caroline Higgins, Sue Hood, Teresa Joseph, Sarah M. Johnson, Manju Kalavala, Mohsen Khorshid, Liberta Labinoti, Ruth Lamb, Nicole Lawson, Alison Layton, Tara Lees, N. J. Levell, Helen S. Lewis, Chris Lovell, Calum C. Lyon, Helen McAteer, Sandy McBride, Sally McCormack, Kevin E. McKenna, Serap Mellor, F. Meredith, Ruth Murphy, P.G. NORRIS, Caroline Owen, Richard Parslew, Gay Perera, Nabil Ponnambath, Urvi Popli (2023). Integrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics. , 152(5), DOI: https://doi.org/10.1016/j.jaci.2023.07.011.
Article57 days agoClinical Impact of Antibodies against Ustekinumab in Psoriasis: An Observational, Cross-Sectional, Multicenter Study
Floris C. Loeff, Teresa Tsakok, Lisanne Dijk, M. Hart, Michael Duckworth, David Baudry, Alice Russell, Nick Dand, Astrid van Leeuwen, Christopher Em Griffiths, Nick J. Reynolds, Juliet N. Barker, A. David Burden, Richard B. Warren, Annick de Vries, Karien Bloem, Gertjan Wolbink, Catherine Smith, Theo Rispens, Juliet N. Barker, Marilyn Benham, A. David Burden, Ian M. Evans, Christopher Em Griffiths, Sagair Hussain, Brian Kirby, Linda Lawson, K.J. Mason, Kathleen McElhone, Ruth Murphy, Anthony D. Ormerod, Caroline Owen, Nick J. Reynolds, Catherine Smith, Richard B. Warren, Juliet N. Barker, Michael R. Barnes, A. David Burden, Paola DiMeglio, Richard Emsley, Andrea Evans, Christopher Em Griffiths, Katherine Payne, Nick J. Reynolds, Catherine Smith, Deborah Stocken, Richard B. Warren (2020). Clinical Impact of Antibodies against Ustekinumab in Psoriasis: An Observational, Cross-Sectional, Multicenter Study. , 140(11), DOI: https://doi.org/10.1016/j.jid.2020.03.957.
Article56 days ago