Bio
We haven't found any bio for you yet.
Researcher Links
Loading links...
Publications by Type
Loading publications…
The last 5 uploaded publications
Abstract 38: Saturated free fatty acids activate a c-Src-JNK1 axis within lipid rafts: Implications for the development of insulin resistance, obesity, and obesity-associated cancer
Ryan G. Holzer, Helen Tran, Giovanni Salinas, Michael Karin (2010). Abstract 38: Saturated free fatty acids activate a c-Src-JNK1 axis within lipid rafts: Implications for the development of insulin resistance, obesity, and obesity-associated cancer. , 70(8_Supplement), DOI: https://doi.org/10.1158/1538-7445.am10-38.
Article80 days agoLoss of acinar cell IKKα triggers spontaneous pancreatitis in mice
Ning Li, Xuefeng Wu, Ryan G. Holzer, Jun Hee Lee, Jelena Todoric, Eek-Joong Park, Hisanobu Ogata, Anna S. Gukovskaya, Ilya Gukovsky, Donald Pizzo, Scott R. VandenBerg, David G. Jackson, Çiğdem Atay, Melek C. Arkan, Thomas J. Deerinck, Jorge Moscat, María T. Díaz‐Meco, David W. Dawson, Mert Erkan, Jörg Kleeff, Michael Karin (2013). Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice. , 123(5), DOI: https://doi.org/10.1172/jci64498.
Article80 days agoSaturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation
Ryan G. Holzer, EekJoong Park, Ning Li, Helen Tran, Monica F. Chen, Crystal Choi, Giovanni Solinas, Michael Karin (2011). Saturated Fatty Acids Induce c-Src Clustering within Membrane Subdomains, Leading to JNK Activation. , 147(1), DOI: https://doi.org/10.1016/j.cell.2011.08.034.
Article80 days agoKinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production
Ewen Gallagher, Thomas Enzler, Atsushi Matsuzawa, Amy Anzelon-Mills, Dennis C. Otero, Ryan G. Holzer, Edith M. Janssen, Min Gao, Michael Karin (2006). Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production. , 8(1), DOI: https://doi.org/10.1038/ni1421.
Article80 days agoDietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
Eek Joong Park, Jun Hee Lee, Guann‐Yi Yu, Guobin He, Syed R. Ali, Ryan G. Holzer, Christoph H. Österreicher, Hiroyuki Takahashi, Michael Karin (2010). Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression. , 140(2), DOI: https://doi.org/10.1016/j.cell.2009.12.052.
Article80 days ago