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The last 5 uploaded publications
Discovery of the Azaserine Biosynthetic Pathway Uncovers a Biological Route for α‐Diazoester Production
Devon Van Cura, Tai L. Ng, Jing Huang, Harry H. Hager, John F Hartwig, Jay D. Keasling, Emily P. Balskus (2023). Discovery of the Azaserine Biosynthetic Pathway Uncovers a Biological Route for α‐Diazoester Production. , 62(28), DOI: https://doi.org/10.1002/anie.202304646.
Article38 days agoComplete integration of carbene-transfer chemistry into biosynthesis
Jing Huang, Andrew F. G. Quest, Pablo Cruz‐Morales, Kai Deng, J.H. Pereira, Devon Van Cura, Ramu Kakumanu, Edward E. K. Baidoo, Qingyun Dan, Yan Chen, Christopher J. Petzold, Trent R. Northen, Paul D. Adams, Douglas S. Clark, Emily P. Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D. Keasling (2023). Complete integration of carbene-transfer chemistry into biosynthesis. , 617(7960), DOI: https://doi.org/10.1038/s41586-023-06027-2.
Article38 days agoAssembly and Evolution of Artificial Metalloenzymes within <i>E. coli</i> Nissle 1917 for Enantioselective and Site-Selective Functionalization of C─H and C═C Bonds
Zhennan Liu, Jing Huang, Yang Gu, Douglas S. Clark, Aindrila Mukhopadhyay, Jay D. Keasling, John F Hartwig (2022). Assembly and Evolution of Artificial Metalloenzymes within <i>E. coli</i> Nissle 1917 for Enantioselective and Site-Selective Functionalization of C─H and C═C Bonds. , 144(2), DOI: https://doi.org/10.1021/jacs.1c10975.
Article38 days agoUnnatural biosynthesis by an engineered microorganism with heterologously expressed natural enzymes and an artificial metalloenzyme
Jing Huang, Zhennan Liu, Brandon J. Bloomer, Douglas S. Clark, Aindrila Mukhopadhyay, Jay D. Keasling, John F Hartwig (2021). Unnatural biosynthesis by an engineered microorganism with heterologously expressed natural enzymes and an artificial metalloenzyme. , 13(12), DOI: https://doi.org/10.1038/s41557-021-00801-3.
Article38 days agoArtificial Biosynthetic Pathway for an Unnatural Terpenoid with an Iridiumcontaining P450
Jing Huang, Zhennan Liu, Brandon J. Bloomer, Douglas S. Clark, Aindrila Mukhopadhyay, Jay D. Keasling, John F Hartwig (2020). Artificial Biosynthetic Pathway for an Unnatural Terpenoid with an Iridiumcontaining P450. , DOI: https://doi.org/10.26434/chemrxiv.11955174.v1.
Preprint38 days ago