0 Datasets
0 Files
Get instant academic access to this publication’s datasets.
Yes. After verification, you can browse and download datasets at no cost. Some premium assets may require author approval.
Files are stored on encrypted storage. Access is restricted to verified users and all downloads are logged.
Yes, message the author after sign-up to request supplementary files or replication code.
Join 50,000+ researchers worldwide. Get instant access to peer-reviewed datasets, advanced analytics, and global collaboration tools.
✓ Immediate verification • ✓ Free institutional access • ✓ Global collaborationJoin our academic network to download verified datasets and collaborate with researchers worldwide.
Get Free AccessAbstract Traditional topical ointment applied on the skin surface has poor drug penetration due to the thickening of the stratum corneum for psoriasis. Microneedles (MNs) provide a desirable opportunity to promote drug penetration. However, the common MNs are difficult to meet the requirement of on‐demand drug delivery. In this study, a smart electrical responsive MNs is fabricated by introducing conductive material of polypyrrole (PPy). Further, a self‐powered controllable transdermal drug delivery system (sc‐TDDS) based on piezoelectric nanogenerator (PENG) is developed. The sc‐TDDS can control drug release by collecting and converting mechanical energy into electrical energy. The sc‐TDDS can release 8.5 ng dexamethasone (Dex) subcutaneously per electrical stimulation. When treating psoriasis‐like skin disease with sc‐TDDS, the inflammatory skin returned to normal after 5 days, which is obviously better than treating with traditional Dex solution coating. This work provides a promising approach of on‐demand transdermal drug release for various disease treatment scenarios.
Yuan Yang, Lingling Xu, Dongjie Jiang, Bo Zhi Chen, Ruizeng Luo, Zhuo Liu, Xuecheng Qu, Chan Wang, Yizhu Shan, Yong Cui, Hui Zheng, Zhiwei Wang, Zhong Lin Wang, Xin Dong Guo, Zhou Li (2021). Self‐Powered Controllable Transdermal Drug Delivery System. , 31(36), DOI: https://doi.org/10.1002/adfm.202104092.
Datasets shared by verified academics with rich metadata and previews.
Authors choose access levels; downloads are logged for transparency.
Students and faculty get instant access after verification.
Type
Article
Year
2021
Authors
15
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1002/adfm.202104092
Access datasets from 50,000+ researchers worldwide with institutional verification.
Get Free Access
