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Get Free AccessWe investigated the effect of a multidomain lifestyle intervention on the risk of dementia estimated using the validated CAIDE risk score (post-hoc analysis). The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) is a 2-year randomized controlled trial among 1,260 at-risk older adults (60-77 years). Difference in the estimated mean change in CAIDE score at 2 years in the intervention compared to the control group was -0.16 (95 %CI -0.31 to 0.00) (p = 0.013), corresponding to a relative dementia risk reduction between 6.04-6.50%. This could be interpreted as a reflection of the prevention potential of the intervention.
Alina Solomon, Ron Handels, Anders Wimo, Riitta Antikaínen, Tiina Laatikainen, Esko Levälahti, Markku Peltonen, Hilkka Soininen, Timo Strandberg, Jaakko Tuomilehto, Miia Kivipelto, Tiia Ngandu (2021). Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk. Journal of Alzheimer s Disease, 82(4), pp. 1461-1466, DOI: 10.3233/jad-210331.
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Type
Letter
Year
2021
Authors
12
Datasets
0
Total Files
0
Language
English
Journal
Journal of Alzheimer s Disease
DOI
10.3233/jad-210331
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