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Get Free AccessSystemic lupus erythematosus (SLE) is characterised by systemic inflammation involving various immune cell types. Monocytes, pivotal in promoting and regulating inflammation in SLE, differentiate from classic monocytes into intermediate and non-classic monocytes, assuming diverse roles and changing their proportions in inflammation. In this study, we investigated the epigenetic and transcriptomic profiles of these and novel monocyte subsets in SLE in relation to activity and progression.
Anna G. Ferreté-Bonastre, Mónica Martínez‐Gallo, Octavio Morante-Palacios, Celia Lourdes Calvillo, Josep Calafell-Segura, Javier Rodríguez‐Ubreva, Manel Esteller, Josefina Cortés-Hernández, Esteban Ballestar (2024). Disease activity drives divergent epigenetic and transcriptomic reprogramming of monocyte subpopulations in systemic lupus erythematosus. , 83(7), DOI: https://doi.org/10.1136/ard-2023-225433.
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Type
Article
Year
2024
Authors
9
Datasets
0
Total Files
0
Language
en
DOI
https://doi.org/10.1136/ard-2023-225433
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