menu_book Explore the article's raw data

The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review

Abstract

BackgroundWhen utilized as an adjunct with antidepressants, antipsychotics, and other psychopharmacological drugs, certain amino acids, such as L-Theanine (LT), have shown potential effectiveness in enhancing the symptomatic outcomes of patients with mental disorders. Despite this, there is a lack of previous systematic reviews examining these associations. Therefore, we conducted a systematic review of randomized controlled trials examining these relationships.MethodsA comprehensive systematic review was conducted, scouring six electronic databases (PubMed, Scopus, PsycINFO, Web of Science, CINAHL Complete, and Cochrane) from their inception up to June 2023, specifically focusing on randomized controlled trials that investigated the effects of LT supplementation on the outcomes of patients with mental health disorders. The Cochrane Risk of Bias Tool for Randomized Trials was employed to assess the quality of the included studies.ResultsAmong the 419 publications identified, 11 studies from six countries - Israel, Iran, the USA, Japan, Australia, and Italy - were included in the final analysis. These studies covered a range of mental disorders, including schizophrenia, Attention-Deficit/Hyperactivity Disorder (ADHD), Obsessive-Compulsive Disorder (OCD), Major Depressive Disorder (MDD), sleep disorders, Generalized Anxiety Disorder (GAD), and Tourette syndrome. The findings demonstrated that LT supplementation reduced psychiatric symptoms more effectively than control conditions in individuals with schizophrenia, anxiety disorders, and ADHD.ConclusionsThe findings from this systematic review suggest that LT supplementation significantly reduced psychiatric symptoms more effectively than control conditions in individuals with schizophrenia, anxiety disorders, and ADHD. However, further studies are essential to validate these findings, deepen the understanding of the observed effects, and explore the mechanisms underlying these associations.

article Review

date_range 2024

language English

link Link of the paper

format_quote

Moshfeghinia Reza

Sanaei Erfan

Mostafavi Sara

Assadian Kasra

Sanaei Ali

Ayano Getinet

Sorry! There is no raw data available for this article.

Loading references...

Loading citations...

Featured Keywords

L-Theanine

Mental disorders

Schizophrenia

ADHD

OCD

MDD

shopping_basket PURCHASE DATA

Performance evaluation of mortar with ground and thermo-activated recycled concrete cement

Abstract

The main objective of this study was to examine the combined effect of ground recycled concrete cement (GRC) and thermo-activated recycled concrete cement (TARC) on properties of mortar. The physical, chemical and microstructural tests were conducted to characterize GRC and TARC before mortar mixtures were produced. The microscopic morphology of GRC and TARC revealed uneven edges and a rough surface that is slightly porous. The GRC and TARC powders were used to replace cement in the range of 0-50% at increments of 10% by volume. The fresh, mechanical, microstructure, and durability characteristics of mortar were tested for different proportion of GRC and TARC as partial replacement of cement. The usage of GRC and TARC decreases the workability of mortar marginally. However, the mechanical performance of the mortar mixtures showed an increasing trend when GRC and TARC share increases in the mixture. Predominantly, compressive strength, bulk density, and ultrasonic pulse velocity (UPV) have all been increased by as much as 20% cement replacement. Furthermore, the incorporation of GRC and TARC enhances the mortar’s durability properties. The microstructure analysis reveals that 20% replacement (GT20) mix has superior structural compactness. In general, partially substitution of GRC and TARC by ordinary Portland cement improves several characteristics of mortar. This will help solve the most prevalent problems that concrete produces, including the high embedded carbon dioxide creation, the high resource usage, and the high waste generation after demolition.

article Article

date_range 2024

language English

link Link of the paper

Compressive Strength

GT0-GT50 (xlsx)