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  5. The effect of immunomodulators on seroconversion after BNT162b2 and AZD1222 vaccines in patients with immune-mediated inflammatory diseases: a prospective cohort study

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Article
en
2022

The effect of immunomodulators on seroconversion after BNT162b2 and AZD1222 vaccines in patients with immune-mediated inflammatory diseases: a prospective cohort study

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en
2022
Vol 188 (4)
Vol. 188
DOI: 10.1093/bjd/ljac109dx.doi.org/10.1093/bjd/ljac109

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Christopher Em Griffiths
Christopher Em Griffiths

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Ali Al‐Janabi
Amelle Ra
Zoe Littlewood
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Abstract

Treatment with nonbiologics, particularly methotrexate, is associated with impaired seroconversion following two BNT162b2 or AZD1222 vaccine doses, in patients with IMIDs. These findings are consistent with those of other published studies. While this could indicate reduced protection against COVID-19, the immunological parameters that correlate most closely with vaccine effectiveness need to be defined to reach this conclusion.

How to cite this publication

Ali Al‐Janabi, Amelle Ra, Zoe Littlewood, Amy Foulkes, H.J.A. Hunter, Hector Chinoy, Christopher A Moriarty, Kimme L Hyrich, Jimmy K. Limdi, Zenas Z N Yiu, Christopher Em Griffiths, Richard B. Warren (2022). The effect of immunomodulators on seroconversion after BNT162b2 and AZD1222 vaccines in patients with immune-mediated inflammatory diseases: a prospective cohort study. , 188(4), DOI: https://doi.org/10.1093/bjd/ljac109.

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Publication Details

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Article

Year

2022

Authors

12

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0

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0

Language

en

DOI

https://doi.org/10.1093/bjd/ljac109

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